Type of Cancer Liver (primary or metastatic), head and neck, kidney 
Route Administered Arterial infusion 
Precautions Four times more active than 5-FU, if liver failure occurs, reduce dose 
Side Effects Hair loss, rash, anemia, low blood counts, loss of appetite, nausea, vomiting, sore mouth and throat, diarrhea, bile salt ioss, thiamine and niacin deficiency